QuickView for K88dsRBP (gene)

Gene Symbol:

ADAR Homo sapiens

Full name:

adenosine deaminase, RNA specific

Synonyms:

ADAR1, AGS6, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88DSRBP, P136, double-stranded RNA-specific adenosine deaminase, 136 kDa double-stranded RNA-binding protein, adenosine deaminase acting on RNA 1-A, dsRNA adenosine deaminase, dsRNA adeonosine deaminase, interferon-induced protein 4, interferon-inducible protein 4

Genomic Location:

Chr 1: 152821157-152867061

Description:

This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ACATTCC_MIR1_MIR206 ,  IRF_Q6 ,  IRF7_01 ,  ICSBP_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1

miRNA binding sites
(Source: miRecords):

hsa-miR-1 Targeted Genes

Cytogenetic Map:

1q21.3

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