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QuickView for NRIP1;jsessionid=2014753A60519F0762E19891B7E966E1 (gene)


Gene Symbol:
NRIP1 Homo sapiens Homo sapiens
Full name:
nuclear receptor interacting protein 1
Synonyms:
RIP140, nuclear receptor-interacting protein 1, nuclear factor RIP140, receptor-interacting protein 140
Genomic Location:
Chr 21: 15255427-15262718
Description:
Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-103 Predicted Gene Targets for miR-125 Predicted Gene Targets for miR-128 Predicted Gene Targets for miR-143 Predicted Gene Targets for miR-186 Predicted Gene Targets for miR-192 Predicted Gene Targets for miR-193 Predicted Gene Targets for miR-194 Predicted Gene Targets for miR-200b Predicted Gene Targets for miR-208
Cytogenetic Map:
chr 21
21q11.2-q21.1





GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | retinoic acid receptor binding | hormone receptor binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | estrogen receptor binding | signaling receptor binding | RNA polymerase II regulatory region DNA binding | androgen receptor binding | DNA binding | sequence-specific double-stranded DNA binding | transcription corepressor activity | nuclear hormone receptor binding | organic cyclic compound binding | retinoid X receptor binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | steroid hormone receptor binding | histone deacetylase binding | transcription coregulator activity | glucocorticoid receptor binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | positive regulation of macromolecule biosynthetic process | developmental process involved in reproduction | gonad development | female gonad development | response to hormone | lipid storage | negative regulation of cellular process | negative regulation of RNA biosynthetic process | androgen receptor signaling pathway | hormone-mediated signaling pathway | positive regulation of cellular biosynthetic process | cellular process | circadian regulation of gene expression | localization | reproductive system development | response to estradiol | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | macromolecule localization | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | gamete generation | regulation of cellular process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | development of primary sexual characteristics | response to stimulus | ovulation | female gamete generation | cellular nitrogen compound biosynthetic process | ovulation cycle | circadian rhythm | development of primary female sexual characteristics | reproduction | rhythmic process | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | steroid hormone mediated signaling pathway | cellular biosynthetic process | ovulation from ovarian follicle | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | regulation of gene expression | response to lipid | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | transcription corepressor activity | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | ovulation cycle process | cell communication | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | multicellular organism reproduction | response to organic substance | anatomical structure development | metabolic process | lipid localization | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | ovarian follicle rupture | cellular response to steroid hormone stimulus | transcription, DNA-templated | intracellular receptor signaling pathway | cellular response to estradiol stimulus | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular macromolecule biosynthetic process | reproductive structure development | developmental process | intracellular steroid hormone receptor signaling pathway | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | female sex differentiation | cellular response to organic substance | sex differentiation | response to steroid hormone | sexual reproduction | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | nucleolus | intracellular organelle | nuclear body | protein-containing complex | histone deacetylase complex | nucleoplasm | chromatin | nuclear chromosome | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular