QuickView for PER1 (gene)
- Gene Symbol:
- PER1
Homo sapiens - Full name:
- period circadian regulator 1
- Synonyms:
- PER, RIGUI, hPER, period circadian protein homolog 1, Period, drosophila, homolog of, circadian clock protein PERIOD 1, circadian pacemaker protein RIGUI, hPER1, period circadian clock 1, period homolog 1
- Genomic Location:
- Chr 17: 7984515-7996427
- Description:
-
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
GABP_B , CMYB_01 , USF_Q6 , CREBP1CJUN_01 , ATF6_01 , CREB_Q4_01 , RYTTCCTG_ETS2_B , ARNT_01 , HOXA4_Q2 , AML_Q6
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
17p13.1
GO Molecular Function
sequence-specific DNA binding | transcription factor activity, transcription factor binding | kinase binding | transcription regulatory region DNA binding | transcription corepressor binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | chromatin binding | ubiquitin-like protein ligase binding | RNA polymerase II regulatory region DNA binding | E-box binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcription factor binding | chromatin DNA binding | ubiquitin protein ligase binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription cofactor binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | negative regulation of JNK cascade | negative regulation of phosphorylation | response to radiation | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | negative regulation of MAPK cascade | regulation of localization | regulation of sodium ion transport | peptidyl-amino acid modification | negative regulation of cellular process | negative regulation of RNA biosynthetic process | histone modification | histone H3 acetylation | negative regulation of protein phosphorylation | histone deacetylation | negative regulation of stress-activated protein kinase signaling cascade | response to organophosphorus | positive regulation of cellular biosynthetic process | cellular process | circadian regulation of gene expression | chromatin organization | negative regulation of signaling | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | negative regulation of glucocorticoid receptor signaling pathway | cellular component organization | histone H4 acetylation | response to stimulus | regulation of intracellular steroid hormone receptor signaling pathway | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | circadian rhythm | peptidyl-lysine acetylation | rhythmic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | protein modification process | cellular biosynthetic process | macromolecule modification | histone H3 deacetylation | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | response to nitrogen compound | response to light stimulus | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | protein acetylation | regulation of MAPK cascade | response to purine-containing compound | regulation of phosphorylation | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | negative regulation of intracellular steroid hormone receptor signaling pathway | regulation of cytokine production involved in inflammatory response | histone acetylation | internal peptidyl-lysine acetylation | biosynthetic process | protein deacetylation | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | negative regulation of stress-activated MAPK cascade | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | protein metabolic process | response to organic substance | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | entrainment of circadian clock | metabolic process | negative regulation of I-kappaB kinase/NF-kappaB signaling | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | peptidyl-lysine modification | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | gene expression | circadian regulation of translation | regulation of phosphate metabolic process | transcription, DNA-templated | regulation of JNK cascade | response to cAMP | negative regulation of protein metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of signal transduction | covalent chromatin modification | regulation of transcription, DNA-templated | response to organic cyclic compound | internal protein amino acid acetylation | cellular protein metabolic process | regulation of cytokine production | cellular macromolecule biosynthetic process | regulation of circadian rhythm | regulation of ion transport | organelle organization | cellular protein modification process | negative regulation of transcription by RNA polymerase II | regulation of transport | positive regulation of transcription, DNA-templated | regulation of hair cycle | positive regulation of nucleic acid-templated transcription | entrainment of circadian clock by photoperiod | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | photoperiodism | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | regulation of translation | regulation of inflammatory response | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of signaling | regulation of p38MAPK cascade | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
