QuickView for Zic5 (gene)
- Gene Symbol:
- ZIC5
Homo sapiens - Full name:
- Zic family member 5
- Synonyms:
- zinc finger protein ZIC 5, Zic family member 5 (odd-paired homolog, Drosophila), zinc finger protein of the cerebellum 5
- Genomic Location:
- Chr 13: 99413276-99422179
- Description:
-
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. The encoded protein may act as a transcriptional repressor. Studies in mouse and Xenopus support a role for this gene in neural crest development. Elevated expression of this gene has been observed in various human cancers and may contribute to cancer progression. This ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
13q32.3
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | nucleic acid binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | ion binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | metal ion binding | heterocyclic compound binding
GO Biological Process
RNA polymerase II transcription factor activity, sequence-specific DNA binding | cell differentiation | nervous system development | cellular process | regulation of cellular process | regulation of metabolic process | regulation of nucleic acid-templated transcription | system development | multicellular organism development | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | anatomical structure development | regulation of RNA biosynthetic process | regulation of transcription, DNA-templated | developmental process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
