Correlation Engine 2.0
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QuickView for aldosterone receptor (gene)

Gene Symbol:
NR3C2 Homo sapiens Homo sapiens
Full name:
nuclear receptor subfamily 3 group C member 2
MCR, MLR, MR, NR3C2VIT, mineralocorticoid receptor, aldosterone receptor, mineralocorticoid receptor 1, mineralocorticoid receptor 2, mineralocorticoid receptor delta, nuclear receptor subfamily 3, group C, member 2 variant 3
Genomic Location:
Chr 4: 149219370-149582973
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseu...
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-101 Predicted Gene Targets for miR-129 Predicted Gene Targets for miR-130 Predicted Gene Targets for miR-135 Predicted Gene Targets for miR-144 Predicted Gene Targets for miR-153 Predicted Gene Targets for miR-186 Predicted Gene Targets for miR-19 Predicted Gene Targets for miR-205 Predicted Gene Targets for miR-30
Cytogenetic Map:
chr 4

GO Molecular Function

sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | nucleic acid binding | lipid binding | steroid hormone receptor activity | DNA binding | signaling receptor activity | ion binding | organic cyclic compound binding | protein binding | zinc ion binding | DNA-binding transcription factor activity | transition metal ion binding | steroid binding | metal ion binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | response to hormone | RNA polymerase II transcription factor activity, sequence-specific DNA binding | hormone-mediated signaling pathway | cellular process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | nitrogen compound metabolic process | regulation of gene expression | response to lipid | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | cell communication | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | response to organic substance | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | cellular response to steroid hormone stimulus | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular macromolecule biosynthetic process | heterocycle metabolic process | cellular metabolic process | cellular response to organic substance | response to steroid hormone | signal transduction | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | receptor complex | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular | membrane