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QuickView for aminopyrine (compound)
PubChem
| Name: | Aminopyrine |
|---|---|
| PubChem Compound ID: | 6009 |
| Description: | A pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of AGRANULOCYTOSIS. A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of CYTOCHROME P-450 metabolic activity in LIVER FUNCTION TESTS. |
| Molecular formula: | C13H17N3O |
| Molecular weight: | 231.294 g/mol |
| Synonyms: |
Pyramidon; C07539; Prestwick0_000088; Aminophenazon; 3H-Pyrazol-3-one, 4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-; Prestwick1_000088; Novamidon; NCGC00016257-01; CAS-58-15-1; Amidophenazone.
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DrugBank
Identification
| Name: | Aminopyrine |
|---|---|
| Name (isomeric): | DB01424 |
| Drug Type: | small molecule |
| Description: | A pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of AGRANULOCYTOSIS. A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of CYTOCHROME P-450 metabolic activity in LIVER FUNCTION TESTS. |
| Synonyms: |
4-Dimethylaminoantipyrine; Dipyrine; Aminopyrine
|
| Category: | Pyrazolones, Analgesics |
| CAS number: | 58-15-1 |
Pharmacology
| Indication: | Formerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water. |
|---|---|
| Pharmacology: | Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of agranulocytosis. A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of cytochrome P-450 metabolic activity in liver function tests. [Wikipedia] |
| Mechanism of Action: | Aminophenazone is metabolized very slowly by normal newborn babies. In older infants, a higher amount of exhaled 13-CO2 is observed. |
| Toxicity: | Can cause life-threatening agranulocytosis. |
| Affected organisms: | Humans and other mammals |
Enzymes
Transporters
