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QuickView for tropicamide (compound)
PubChem
| Name: | Tropicamide |
|---|---|
| PubChem Compound ID: | 5593 |
| Description: | One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic. |
| Molecular formula: | C17H20N2O2 |
| Molecular weight: | 284.353 g/mol |
| Synonyms: |
Epitromina; DivK1c_000448; 1508-75-4; Spectrum2_000936; Tropikamid; Minims tropicamide; D00397; EU-0101223; KBio3_001509; Spectrum3_000655.
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DrugBank
Identification
| Name: | Tropicamide |
|---|---|
| Name (isomeric): | DB00809 |
| Drug Type: | small molecule |
| Description: | One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic. |
| Synonyms: |
Tropicamid
|
| Brand: | I-Picamide, Tropicacyl, Mydriacyl, Spectro-Cyl, Mydriafair, Ocu-Tropic, Mydriaticum, Paremyd, Opticyl, Minims Tropicamide |
| Brand name mixture: | Phenyltrope Oph Soln(Phenylephrine Hydrochloride + Tropicamide), Diophenyl-T Solution(Phenylephrine Hydrochloride + Tropicamide) |
| Category: | Muscarinic Antagonists, Mydriatics, Diagnostic aid, mydriatic, Diagnostic aid, cycloplegic |
| CAS number: | 1508-75-4 |
Pharmacology
| Indication: | Indicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye. |
|---|---|
| Pharmacology: |
Tropicamide belongs to the group of medicines called anti-muscarinics. Tropicamide blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. By blocking these receptors, tropicamide produces dilatation of the pupil (mydriasis) and prevents the eye from a...
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| Mechanism of Action: | Tropicamide binds to and blocks the receptors in the muscles of the eye (muscarinic receptor M4). Tropicamide acts by blocking the responses of the iris sphincter muscle to the iris and ciliary muscles to cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle. |
| Protein binding: | 45% |
| Toxicity: | Overdose can casue dry mouth, blurred vision, photophobia, hallucinations and rapid/irregular pulse. |
| Affected organisms: | Humans and other mammals |
Targets
