QuickView for HMGA1a;jsessionid=1B2D681F08E39A46B1144F9EB8756C5F (gene)
- Gene Symbol:
- Hmga1
Rattus norvegicus - Full name:
- high mobility group AT-hook 1
- Synonyms:
- Hmgi, Hmgiy, high mobility group protein HMG-I/HMG-Y, HMG-I(Y), high mobility group AT-hook protein 1, high mobility group protein A1
- Genomic Location:
- Chr 20: 5769052-5772269
- Description:
-
expressed in metastatic prostate tumors; may be associated with transformation
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
| Transcripts Names |
|---|
| NM_139327 |
| XM_006256157 |
| XM_006256162 |
| XM_006256156 |
| XM_017601532 |
| XM_006256164 |
| XM_006256163 |
| XM_006256158 |
GO Molecular Function
sequence-specific DNA binding | DNA-(apurinic or apyrimidinic site) endonuclease activity | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enhancer binding | retinoic acid receptor binding | hormone receptor binding | enzyme binding | nucleic acid binding | signaling receptor binding | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | lyase activity | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | catalytic activity | chromatin binding | enhancer sequence-specific DNA binding | DNA binding | sequence-specific double-stranded DNA binding | nuclear hormone receptor binding | organic cyclic compound binding | retinoid X receptor binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | nuclear receptor transcription coactivator activity | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | 5'-deoxyribose-5-phosphate lyase activity | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | transcription coregulator activity | AT DNA binding | heterocyclic compound binding | peroxisome proliferator activated receptor binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | response to virus | positive regulation of cell aging | regulation of cell aging | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | male gamete generation | positive regulation of cellular biosynthetic process | cellular process | chromatin organization | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | gamete generation | senescence-associated heterochromatin focus assembly | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | reproduction | cellular nitrogen compound metabolic process | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | DNA repair | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | heterochromatin organization | response to external biotic stimulus | nitrogen compound metabolic process | reproductive process | cellular response to DNA damage stimulus | regulation of gene expression | cellular response to stress | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | chromatin remodeling | base-excision repair | transcription coactivator activity | regulation of RNA metabolic process | cell aging | multicellular organism reproduction | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | DNA metabolic process | chromatin assembly or disassembly | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nuclear receptor transcription coactivator activity | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | DNA packaging | transcription, DNA-templated | chromatin assembly | cellular senescence | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | response to biotic stimulus | regulation of developmental process | positive regulation of cellular senescence | developmental process | organelle organization | spermatogenesis | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | DNA conformation change | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | heterochromatin assembly | aging | sexual reproduction | response to other organism | positive regulation of gene expression | macromolecule metabolic process | regulation of cellular senescence | multicellular organismal process | oncogene-induced cell senescence
GO Cellular Component
nuclear transcription factor complex | chromosome | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | senescence-associated heterochromatin focus | cell | transcription factor complex | intracellular organelle | protein-containing complex | chromatin | membrane-bounded organelle | heterochromatin | nucleus | organelle | intracellular
