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QuickView for HSF1;jsessionid=7A8B59A13542A1C512EAB8F98BE75705;jsessionid=E8BDCB60BED316F882990F4D7D162454;jsessionid=ECB61E37CF3CCD738144032722413E91 (gene)


Gene Symbol:
HSF1 Bos taurus Bos taurus
Full name:
heat shock transcription factor 1
Synonyms:
MGC143130
Genomic Location:
Chr 14: 448053-453004
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_001076809
Protein Names
Q08DJ8



GO Molecular Function

sequence-specific DNA binding | protein self-association | kinase binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | protein kinase binding | proximal promoter sequence-specific DNA binding | enzyme binding | intronic transcription regulatory region sequence-specific DNA binding | nucleic acid binding | chromatin binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | promoter-specific chromatin binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | identical protein binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | chromatin DNA binding | intronic transcription regulatory region DNA binding | protein dimerization activity | translation elongation factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | Hsp90 protein binding | heat shock protein binding | heterocyclic compound binding | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding

GO Biological Process

RNA metabolic process | protein homooligomerization | response to radiation | positive regulation of macromolecule biosynthetic process | RNA processing | response to lipopolysaccharide | developmental process involved in reproduction | intracellular signal transduction | establishment of localization | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | response to metal ion | regulation of mRNA polyadenylation | male gamete generation | response to drug | response to antibiotic | negative regulation of DNA metabolic process | regulation of DNA repair | regulation of mRNA processing | positive regulation of cellular biosynthetic process | cellular process | localization | reproductive system development | female pregnancy | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | macromolecule localization | regulation of cell cycle | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | response to inorganic substance | negative regulation of cellular metabolic process | regulation of binding | gamete generation | cellular response to diamide | regulation of cellular process | regulation of metabolic process | negative regulation of DNA repair | negative regulation of tumor necrosis factor production | organic cyclic compound metabolic process | RNA biosynthetic process | cellular response to unfolded protein | response to topologically incorrect protein | cellular aromatic compound metabolic process | cellular component organization | MAPK cascade | cellular response to topologically incorrect protein | cellular response to metal ion | cellular response to salt | response to stimulus | female gamete generation | positive regulation of cold-induced thermogenesis | regulation of cellular response to heat | signal transduction by protein phosphorylation | response to stress | negative regulation of tumor necrosis factor superfamily cytokine production | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | regulation of double-strand break repair | protein homotrimerization | reproduction | cellular response to inorganic substance | response to temperature stimulus | cellular response to cadmium ion | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | cellular response to toxic substance | positive regulation of transcription from RNA polymerase II promoter in response to heat stress | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | positive regulation of mRNA processing | protein modification process | mRNA metabolic process | cellular biosynthetic process | positive regulation of multicellular organism growth | embryo development | macromolecule modification | response to herbicide | embryonic placenta development | DNA repair | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | response to nitrogen compound | response to external biotic stimulus | system development | nitrogen compound metabolic process | reproductive process | cellular response to antibiotic | multicellular organism development | phosphorus metabolic process | cellular response to DNA damage stimulus | protein complex oligomerization | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of gene expression | organic substance transport | cellular response to stress | response to lipid | cell cycle | cellular response to heat | negative regulation of cytokine production | positive regulation of cellular metabolic process | cellular response to radiation | regulation of mRNA 3'-end processing | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | cellular response to gamma radiation | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of double-strand break repair | negative regulation of double-strand break repair via nonhomologous end joining | biosynthetic process | response to cadmium ion | positive regulation of mRNA polyadenylation | aromatic compound biosynthetic process | positive regulation of transcription from RNA polymerase II promoter in response to stress | mRNA transport | phosphorylation | cellular protein-containing complex assembly | response to toxic substance | establishment of RNA localization | protein phosphorylation | regulation of tumor necrosis factor production | response to gamma radiation | phosphate-containing compound metabolic process | cellular response to drug | response to bacterium | chordate embryonic development | cell communication | regulation of cellular metabolic process | protein trimerization | positive regulation of cell proliferation | mRNA transcription | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | regulation of double-strand break repair via nonhomologous end joining | response to insecticide | regulation of mitotic cell cycle | multicellular organism reproduction | protein-containing complex assembly | protein metabolic process | DNA-binding transcription factor activity | regulation of growth | response to organic substance | DNA metabolic process | response to antineoplastic agent | anatomical structure development | regulation of protein heterodimerization activity | nucleobase-containing compound transport | nuclear division | metabolic process | regulation of DNA-templated transcription in response to stress | cellular response to arsenic-containing substance | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | embryonic organ development | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | organic substance metabolic process | response to copper ion | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | response to heat | cellular response to ionizing radiation | positive regulation of mRNA 3'-end processing | transcription, DNA-templated | RNA transport | meiotic cell cycle | response to arsenic-containing substance | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of transcription, DNA-templated | regulation of protein binding | regulation of developmental growth | cellular protein metabolic process | regulation of transcription from RNA polymerase II promoter in response to stress | response to unfolded protein | regulation of cytokine production | cellular macromolecule biosynthetic process | response to biotic stimulus | reproductive structure development | regulation of developmental process | developmental process | organelle organization | spermatogenesis | cellular protein modification process | response to salt | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | embryonic process involved in female pregnancy | cellular response to sodium arsenite | in utero embryonic development | positive regulation of metabolic process | cellular metabolic process | mRNA processing | placenta development | cellular response to organic substance | cellular response to copper ion | RNA localization | sexual reproduction | response to ionizing radiation | response to other organism | signal transduction | female meiotic nuclear division | positive regulation of gene expression | response to sodium arsenite | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | nuclear stress granule | microtubule organizing center | chromosome, centromeric region | condensed chromosome, centromeric region | cell | nuclear lumen | ribonucleoprotein granule | kinetochore | cytoplasm | spindle | intracellular organelle | nuclear body | centrosome | protein-containing complex | pronucleus | PML body | nucleoplasm | ribonucleoprotein complex | condensed chromosome kinetochore | perinuclear region of cytoplasm | microtubule cytoskeleton | spindle pole | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | cytoskeleton | mitotic spindle pole | intracellular | mitotic spindle | condensed chromosome