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QuickView for IKLF;jsessionid=0410C7BE7B231C4D611712553C02776E (gene)


Gene Symbol:
Klf5 Rattus norvegicus Rattus norvegicus
Full name:
Kruppel-like factor 5
Synonyms:
Bteb2, IKLF, bteb2, Krueppel-like factor 5, Kruppel-like factor 5 (intestinal), basic transcription element binding protein 2, basic transcription element binding protein BTEB2
Genomic Location:
Chr 15: 83103177-83118363
Description:
mouse homolog is a transcription factor involved in positive regulation of cellular proliferation
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
AAAYRNCTG_UNKNOWN CMYB_01 GATA3_01 EVI1_04 CEBPB_01 TST1_01 MYB_Q6 GR_Q6 CEBP_C HAND1E47_01
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_053394
XM_006252403
Protein Names
Q66HP1



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | response to cytokine | muscle tissue development | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | blood vessel morphogenesis | positive regulation of cellular biosynthetic process | cellular process | negative regulation of cardiac vascular smooth muscle cell differentiation | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of fat cell differentiation | regulation of cell differentiation | muscle structure development | skeletal muscle organ development | regulation of cellular process | negative regulation of cardiocyte differentiation | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | cellular component organization | regulation of vasculature development | response to stimulus | vasculature development | skeletal muscle tissue development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | response to peptide | epithelial cell development | cardiovascular system development | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | intestinal epithelial cell development | cellular biosynthetic process | cell-cell signaling | blood vessel development | regulation of nucleic acid-templated transcription | response to nitrogen compound | regulation of cell projection assembly | system development | nitrogen compound metabolic process | multicellular organism development | regulation of gene expression | cellular response to peptide | cell-cell signaling via exosome | cell projection assembly | positive regulation of cellular metabolic process | regulation of smooth muscle cell differentiation | regulation of pri-miRNA transcription by RNA polymerase II | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | negative regulation of smooth muscle cell differentiation | cellular response to cytokine stimulus | biosynthetic process | aromatic compound biosynthetic process | angiogenesis | microvillus assembly | positive regulation of pri-miRNA transcription by RNA polymerase II | digestive tract development | microvillus organization | striated muscle tissue development | cell communication | regulation of cellular metabolic process | positive regulation of cell proliferation | regulation of RNA metabolic process | intestinal epithelial cell differentiation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | response to organic substance | regulation of microvillus assembly | digestive system development | anatomical structure development | cell projection organization | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | negative regulation of vascular smooth muscle cell differentiation | transcription, DNA-templated | anatomical structure formation involved in morphogenesis | cellular response to leukemia inhibitory factor | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of fat cell differentiation | regulation of developmental process | developmental process | regulation of muscle cell differentiation | columnar/cuboidal epithelial cell development | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | negative regulation of vasculature development | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | negative regulation of muscle cell differentiation | positive regulation of metabolic process | regulation of cell projection organization | cellular metabolic process | cellular response to organic substance | circulatory system development | skeletal muscle cell differentiation | negative regulation of cell differentiation | regulation of cellular component organization | muscle organ development | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | Golgi apparatus | endomembrane system | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular