QuickView for NeuroD2;jsessionid=20054EC388368883D891BA35EB7E7D29;jsessionid=EAEB0666DFE843CF70E25AEA9B4565E7;jsessionid=763F3E35B1D269E2EF7E3EB0C21F7A86;jsessionid=0CA832612D1A9BCDBAE43ED8FD6CC0FE;jsessionid=D5A16ABCF92A8A2464AAC6D55253D6DD (gene)

Gene Symbol:

NEUROD2 Homo sapiens

Full name:

neuronal differentiation 2

Synonyms:

NDRF, bHLHa1, neurogenic differentiation factor 2, class A basic helix-loop-helix protein 1, neuroD-related factor, neurogenic basic-helix-loop-helix protein, neurogenic differentiation 2

Genomic Location:

Chr 17: 35013547-35017701

Description:

This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuron...

View Full Description

This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CGTSACG_PAX3_B ,  GATTGGY_NFY_Q6_01 ,  NFMUE1_Q6 ,  FREAC7_01 ,  HNF3ALPHA_Q6 ,  MAZR_01 ,  TAL1ALPHAE47_01 ,  TCANNTGAY_SREBP1_01 ,  ARNT_01 ,  TGGNNNNNNKCCAR_UNKNOWN ,  FOX_Q2 ,  HFH3_01 ,  EFC_Q6 ,  VDR_Q3 ,  MYOGNF1_01 ,  HEN1_01 ,  MYCMAX_03 ,  CATTGTYY_SOX9_B1 ,  YGACNNYACAR_UNKNOWN ,  FOXD3_01 ,  EVI1_04 ,  XBP1_01 ,  STAT6_01 ,  ARNT_02 ,  FAC1_01 ,  SREBP1_Q6 ,  RYCACNNRNNRNCAG_UNKNOWN ,  WTGAAAT_UNKNOWN ,  OSF2_Q6 ,  GGGAGGRR_MAZ_Q6 ,  MYCMAX_02 ,  OCT1_Q6 ,  TAL1BETAE47_01 ,  SOX9_B1 ,  DBP_Q6 ,  PAX4_02 ,  GTGACGY_E4F1_Q6 ,  GGATTA_PITX2_Q2 ,  FREAC3_01 ,  RREB1_01 ,  AP4_01 ,  EGR_Q6 ,  NKX62_Q2 ,  HNF3_Q6 ,  HNF3B_01 ,  FOXJ2_01 ,  GGGCGGR_SP1_Q6 ,  STAT5A_03 ,  CCCNNGGGAR_OLF1_01 ,  E2F1_Q3_01 ,  NKX61_01 ,  TGCCAAR_NF1_Q6 ,  HFH4_01 ,  MEIS1_01 ,  TGTTTGY_HNF3_Q6 ,  HFH8_01 ,  AHRARNT_01 ,  TCTCTCC_MIR185 ,  NMYC_01 ,  USF_Q6_01 ,  GATGKMRGCG_UNKNOWN ,  TTGTTT_FOXO4_01 ,  CCAGGGG_MIR331 ,  HEN1_02 ,  SREBP_Q3 ,  GTGGGTGK_UNKNOWN ,  TAL1BETAITF2_01 ,  TGACAGNY_MEIS1_01 ,  CTTTGT_LEF1_Q2 ,  EGR1_01 ,  CAGCTG_AP4_Q5 ,  CACBINDINGPROTEIN_Q6 ,  MZF1_02 ,  PAX4_03 ,  YNGTTNNNATT_UNKNOWN ,  PPARA_02 ,  HNF6_Q6 ,  GGGTGGRR_PAX4_03 ,  OLF1_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-185 ,  Predicted Gene Targets for miR-331

Cytogenetic Map:

17q12

search → result