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QuickView for PTX;jsessionid=BFF7E5949E3331FEB41DA8FF7A7B02D7;jsessionid=92840E74E06F3853F531AD5210C290D9;jsessionid=7E2C4674166D8C591ABC03FCBF2785B1 (gene)


Gene Symbol:
pitx2 Danio rerio Danio rerio
Full name:
paired-like homeodomain transcription factor 2
Synonyms:
MGC110508, pitx2a, pitx2c, zgc:110508
Genomic Location:
Chr 14: 41082559-41086112
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
CMYB_01 AP4_01 AACTTT_UNKNOWN CREB_01 CREBP1CJUN_01 IRF1_01 CDP_02 CEBPB_01 CREB_02 CEBPB_02


Transcripts Names
NM_130975
Protein Names
Q9W5Z1
Q9W5Z2
Q568C4



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | brain development | cornea development in camera-type eye | positive regulation of macromolecule biosynthetic process | determination of left/right asymmetry in diencephalon | cranial skeletal system development | morphogenesis of an epithelium | embryonic viscerocranium morphogenesis | eye development | RNA polymerase II transcription factor activity, sequence-specific DNA binding | embryonic camera-type eye morphogenesis | nervous system development | left/right pattern formation | retinoic acid receptor signaling pathway | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | odontogenesis | determination of left/right symmetry | mesoderm development | optic cup morphogenesis involved in camera-type eye development | positive regulation of nitrogen compound metabolic process | diencephalon development | tissue development | regulation of cellular process | regulation of metabolic process | head morphogenesis | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | head development | response to stimulus | cellular nitrogen compound biosynthetic process | embryonic skeletal system development | cellular nitrogen compound metabolic process | blood circulation | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of RNA biosynthetic process | cellular biosynthetic process | embryo development | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | multicellular organism development | determination of bilateral symmetry | regulation of gene expression | positive regulation of cellular metabolic process | animal organ morphogenesis | determination of left/right asymmetry in nervous system | regulation of nitrogen compound metabolic process | regulation of vascular permeability | regulation of transcription by RNA polymerase II | morphogenesis of an epithelial sheet | embryonic camera-type eye development | biosynthetic process | aromatic compound biosynthetic process | digestive tract development | sensory organ development | chordate embryonic development | cell communication | regulation of cellular metabolic process | eye morphogenesis | skeletal system morphogenesis | mesendoderm development | heart development | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | embryonic morphogenesis | embryonic organ morphogenesis | embryonic cranial skeleton morphogenesis | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | regionalization | tissue morphogenesis | digestive system development | face morphogenesis | embryonic heart tube development | anatomical structure development | closure of optic fissure | epithalamus development | embryonic skeletal system morphogenesis | metabolic process | regulation of RNA biosynthetic process | embryonic organ development | morphogenesis of embryonic epithelium | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | embryonic heart tube left/right pattern formation | embryonic camera-type eye formation | organic substance metabolic process | animal organ development | forebrain development | gene expression | transcription, DNA-templated | intracellular receptor signaling pathway | camera-type eye development | anatomical structure formation involved in morphogenesis | signaling | regulation of transcription, DNA-templated | endoderm development | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | camera-type eye morphogenesis | developmental process | habenula development | determination of digestive tract left/right asymmetry | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | prechordal plate formation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | skeletal system development | cellular metabolic process | body morphogenesis | embryonic eye morphogenesis | circulatory system development | signal transduction | positive regulation of gene expression | iris morphogenesis | macromolecule metabolic process | multicellular organismal process | face development

GO Cellular Component

intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular