QuickView for RAD50;jsessionid=37628AE0B67F876B932AC56C8152231E;jsessionid=8A67C7A97FC0AC931E92106B8247F305 (gene)
- Gene Symbol:
- Rad50
Mus musculus - Full name:
- RAD50 double strand break repair protein
- Synonyms:
- Mrell, Rad50l, DNA repair protein RAD50, RAD50 homolog, mRad50
- Genomic Location:
- Chr 11: 53463072-53520799
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | adenylate kinase activity | nuclease activity | nucleoside monophosphate kinase activity | sequence-specific single stranded DNA binding | single-stranded DNA endodeoxyribonuclease activity | cation binding | nucleic acid binding | ribonucleotide binding | ATP-dependent DNA helicase activity | nucleotide binding | hydrolase activity | single-stranded DNA binding | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | protein binding, bridging | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | deoxyribonuclease activity | DNA binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | ATP-dependent helicase activity | ion binding | nucleobase-containing compound kinase activity | organic cyclic compound binding | double-stranded telomeric DNA binding | endodeoxyribonuclease activity | molecular adaptor activity | G-quadruplex DNA binding | purine ribonucleoside triphosphate binding | DNA helicase activity | protein binding | double-stranded DNA binding | transferase activity, transferring phosphorus-containing groups | 3'-5' exonuclease activity | hydrolase activity, acting on acid anhydrides | phosphotransferase activity, phosphate group as acceptor | endonuclease activity | transferase activity | single-stranded telomeric DNA binding | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | helicase activity | drug binding | kinase activity | exonuclease activity | metal ion binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | telomeric DNA binding | small molecule binding
GO Biological Process
double-strand break repair | telomere maintenance | positive regulation of cellular component organization | adenylate kinase activity | nuclease activity | nucleoside monophosphate kinase activity | negative regulation of cellular process | telomere capping | positive regulation of phosphate metabolic process | regulation of organelle organization | negative regulation of DNA metabolic process | cellular process | telomere maintenance via telomerase | single-stranded DNA endodeoxyribonuclease activity | nucleotide metabolic process | negative regulation of viral life cycle | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | nucleoside monophosphate phosphorylation | negative regulation of cellular metabolic process | DNA geometric change | anatomical structure homeostasis | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | cellular component organization | ATP-dependent DNA helicase activity | regulation of telomere capping | response to stimulus | regulation of DNA recombination | positive regulation of protein metabolic process | response to stress | cellular nitrogen compound biosynthetic process | reproduction | cellular nitrogen compound metabolic process | telomere organization | nucleic acid phosphodiester bond hydrolysis | negative regulation of metabolic process | cellular component assembly | cellular biosynthetic process | DNA recombination | telomere maintenance via telomere lengthening | nucleotide biosynthetic process | DNA repair | regulation of viral entry into host cell | nitrogen compound metabolic process | reproductive process | positive regulation of organelle organization | phosphorus metabolic process | cellular response to DNA damage stimulus | protein complex oligomerization | regulation of telomere maintenance | regulation of catalytic activity | regulation of phosphorylation | positive regulation of chromosome organization | DNA biosynthetic process | cellular response to stress | cell cycle | regulation of protein autophosphorylation | organophosphate metabolic process | RNA-dependent DNA biosynthetic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | deoxyribonuclease activity | regulation of nitrogen compound metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | negative regulation of viral process | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | phosphorylation | nucleobase-containing compound kinase activity | phosphate-containing compound metabolic process | DNA duplex unwinding | DNA strand elongation | regulation of cellular metabolic process | endodeoxyribonuclease activity | regulation of protein metabolic process | homeostatic process | regulation of protein phosphorylation | negative regulation of telomere maintenance | regulation of viral process | regulation of mitotic cell cycle | DNA helicase activity | positive regulation of molecular function | protein-containing complex assembly | positive regulation of protein modification process | negative regulation of viral entry into host cell | telomeric 3' overhang formation | regulation of kinase activity | DNA metabolic process | metabolic process | 3'-5' exonuclease activity | regulation of mitotic recombination | nucleobase-containing compound metabolic process | organic substance metabolic process | endonuclease activity | positive regulation of kinase activity | mitotic recombination | regulation of phosphate metabolic process | regulation of chromosome organization | chromosome organization involved in meiotic cell cycle | telomere maintenance via recombination | meiotic cell cycle | negative regulation of chromosome organization | positive regulation of phosphorylation | protein heterooligomerization | cellular macromolecule biosynthetic process | positive regulation of telomere maintenance | positive regulation of DNA metabolic process | kinase activity | negative regulation of telomere capping | organelle organization | positive regulation of protein autophosphorylation | exonuclease activity | DNA conformation change | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | regulation of viral life cycle | regulation of cellular component organization | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
condensed nuclear chromosome | site of DNA damage | chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | inclusion body | protein-containing complex | pronucleus | nucleoplasm | chromatin | nuclear chromosome | perinuclear region of cytoplasm | chromosome, telomeric region | site of double-strand break | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | nuclear chromosome, telomeric region | intracellular | Mre11 complex | condensed chromosome
