QuickView for RB1;jsessionid=BB236F7730C72FD55BC405789529EDCF;jsessionid=D94FFE889552B6A1BE40353C8B003E21 (gene)
- Gene Symbol:
- RB1
Bos taurus - Full name:
- retinoblastoma 1
- Synonyms:
- P105-RB, PP110, RB11
- Genomic Location:
- Chr 12: 17508776-17628174
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
sequence-specific DNA binding | kinase binding | transcription regulatory region DNA binding | proximal promoter sequence-specific DNA binding | enzyme binding | RNA polymerase II activating transcription factor binding | nucleic acid binding | disordered domain specific binding | importin-alpha family protein binding | protein domain specific binding | ubiquitin-like protein ligase binding | DNA binding | sequence-specific double-stranded DNA binding | identical protein binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | phosphoprotein binding | protein binding | double-stranded DNA binding | transcription factor binding | ubiquitin protein ligase binding | RNA polymerase II transcription factor binding | activating transcription factor binding | heterocyclic compound binding
GO Biological Process
negative regulation of phosphorylation | regulation of supramolecular fiber organization | cell morphogenesis | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | regulation of cellular localization | muscle tissue development | intracellular signal transduction | regulation of localization | regulation of cell cycle G1/S phase transition | erythrocyte homeostasis | epithelial cell apoptotic process | regulation of immune system process | myeloid cell differentiation | neuron death | negative regulation of cellular process | negative regulation of kinase activity | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | nervous system development | regulation of extracellular matrix organization | negative regulation of protein phosphorylation | regulation of G1/S transition of mitotic cell cycle | neurogenesis | regulation of organelle organization | generation of neurons | tissue homeostasis | enucleate erythrocyte differentiation | regulation of chromosome segregation | positive regulation of cellular biosynthetic process | cellular process | negative regulation of inflammatory response | localization | cell maturation | negative regulation of signaling | neuron development | negative regulation of G1/S transition of mitotic cell cycle | regulation of mitotic nuclear division | immune system development | negative regulation of nucleic acid-templated transcription | regulation of chromosome separation | macromolecule localization | regulation of cell cycle | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | negative regulation of myofibroblast differentiation | regulation of smoothened signaling pathway | negative regulation of cellular metabolic process | tissue development | regulation of binding | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | muscle structure development | anatomical structure homeostasis | muscle cell differentiation | skeletal muscle organ development | regulation of cellular process | regulation of metabolic process | positive regulation of extracellular matrix organization | positive regulation of cell cycle phase transition | small GTPase mediated signal transduction | cellular component organization | response to stimulus | positive regulation of collagen fibril organization | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | regulation of mitotic cell cycle phase transition | chromosome segregation | positive regulation of immune system process | sister chromatid biorientation | cellular response to xenobiotic stimulus | negative regulation of protein kinase activity | skeletal muscle tissue development | regulation of cell proliferation | multicellular organismal homeostasis | regulation of cell cycle phase transition | programmed cell death | regulation of transcription regulatory region DNA binding | cellular localization | cell cycle G1/S phase transition | regulation of DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | myeloid cell homeostasis | positive regulation of macrophage differentiation | regulation of nucleic acid-templated transcription | apoptotic process | system development | regulation of signal transduction | negative regulation of mitotic cell cycle phase transition | positive regulation of organelle organization | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | positive regulation of mitotic metaphase/anaphase transition | positive regulation of chromosome separation | sister chromatid segregation | negative regulation of cold-induced thermogenesis | regulation of catalytic activity | regulation of phosphorylation | maintenance of mitotic sister chromatid cohesion | positive regulation of chromosome organization | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of gene expression | mitotic sister chromatid cohesion | cell cycle | positive regulation of cellular metabolic process | glial cell apoptotic process | regulation of mitotic sister chromatid separation | regulation of nitrogen compound metabolic process | neuron apoptotic process | regulation of transcription by RNA polymerase II | protein localization to organelle | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | regulation of cohesin loading | homeostasis of number of cells | cell division | aortic valve morphogenesis | regulation of cellular protein metabolic process | hepatocyte apoptotic process | digestive tract development | response to xenobiotic stimulus | mitotic cell cycle phase transition | cell morphogenesis involved in differentiation | nuclear chromosome segregation | regulation of lipid kinase activity | striated muscle tissue development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | semi-lunar valve development | regulation of protein metabolic process | regulation of transcription involved in G1/S transition of mitotic cell cycle | heart development | homeostatic process | G1/S transition of mitotic cell cycle | regulation of protein phosphorylation | regulation of RNA metabolic process | striated muscle cell differentiation | regulation of mitotic cell cycle | neuron maturation | positive regulation of molecular function | regulation of sister chromatid cohesion | neuron differentiation | heart valve development | negative regulation of epithelial cell proliferation | regulation of growth | digestive system development | regulation of hemopoiesis | cell cycle arrest | protein localization to chromosome, centromeric region | regulation of kinase activity | regulation of sister chromatid segregation | anatomical structure development | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | nuclear division | cell projection organization | positive regulation of supramolecular fiber organization | regulation of RNA biosynthetic process | developmental maturation | negative regulation of transcription, DNA-templated | negative regulation of mitotic cell cycle | cellular protein localization | neuron projection development | heart valve morphogenesis | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | negative regulation of cellular protein metabolic process | positive regulation of chromosome segregation | regulation of phosphate metabolic process | regulation of chromosome organization | mitotic nuclear division | positive regulation of binding | attachment of spindle microtubules to kinetochore | negative regulation of cell cycle | regulation of protein localization to chromatin | negative regulation of protein metabolic process | regulation of mitotic sister chromatid segregation | regulation of cell communication | negative regulation of cell cycle G1/S phase transition | regulation of macrophage differentiation | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | myoblast differentiation | cell development | positive regulation of DNA binding | protein localization | regulation of epithelial cell proliferation | anatomical structure morphogenesis | cellular macromolecule localization | regulation of developmental process | developmental process | organelle organization | negative regulation of smoothened signaling pathway | erythrocyte differentiation | positive regulation of cell cycle process | regulation of cell growth | sister chromatid cohesion | positive regulation of mitotic sister chromatid separation | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | aortic valve development | negative regulation of cell proliferation | regulation of mitotic metaphase/anaphase transition | Ras protein signal transduction | positive regulation of nucleic acid-templated transcription | cell cycle phase transition | positive regulation of transcription by RNA polymerase II | regulation of lipid metabolic process | positive regulation of metabolic process | chromosome organization | positive regulation of myeloid leukocyte differentiation | immune system process | hematopoietic or lymphoid organ development | negative regulation of cell cycle process | regulation of protein localization | circulatory system development | regulation of inflammatory response | mitotic sister chromatid segregation | skeletal muscle cell differentiation | negative regulation of cell differentiation | regulation of cellular component organization | negative regulation of transcription involved in G1/S transition of mitotic cell cycle | muscle organ development | positive regulation of mitotic nuclear division | protein localization to chromosome | signal transduction | regulation of signaling | positive regulation of gene expression | positive regulation of transcription regulatory region DNA binding | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
nuclear transcription factor complex | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | transcription elongation factor complex | protein kinase complex | cell | nuclear lumen | transcription factor complex | Rb-E2F complex | cyclin/CDK positive transcription elongation factor complex | spindle | intracellular organelle | nuclear body | carboxy-terminal domain protein kinase complex | protein-containing complex | PML body | nucleoplasm | nuclear cyclin-dependent protein kinase holoenzyme complex | transferase complex | microtubule cytoskeleton | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cyclin-dependent protein kinase holoenzyme complex | cytoskeleton | intracellular
