QuickView for RBR-2;jsessionid=D75B3EBA8F2B27F2523007FA3911E340;jsessionid=6582004E436FCFFD50E63C6C81E2B5FB;jsessionid=B0E61A59DCD4A935A0F05EE3B17E51D2 (gene)
- Gene Symbol:
- Kdm5b
Rattus norvegicus - Full name:
- lysine demethylase 5B
- Synonyms:
- Jarid1b, RGD1565602, lysine-specific demethylase 5B, Jumonji, AT rich interactive domain 1B (RBP2-like), jumonji, AT rich interactive domain 1B (Rbp2 like), lysine (K)-specific demethylase 5B
- Genomic Location:
- Chr 13: 47502600-47576954
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
| Protein Names |
|---|
| No proteins found. |
GO Molecular Function
sequence-specific DNA binding | histone demethylase activity (H3-dimethyl-K4 specific) | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | cation binding | nucleic acid binding | demethylase activity | histone demethylase activity (H3-trimethyl-K4 specific) | methylated histone binding | catalytic activity | chromatin binding | modification-dependent protein binding | DNA binding | sequence-specific double-stranded DNA binding | transcription corepressor activity | histone demethylase activity (H3-K4 specific) | histone demethylase activity | ion binding | organic cyclic compound binding | protein binding | zinc ion binding | double-stranded DNA binding | DNA-binding transcription factor activity | histone binding | transition metal ion binding | transcription coregulator activity | metal ion binding | heterocyclic compound binding
GO Biological Process
mammary duct terminal end bud growth | histone demethylase activity (H3-dimethyl-K4 specific) | response to cytokine | developmental process involved in reproduction | regulation of localization | mammary gland duct morphogenesis | morphogenesis of an epithelium | eye development | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | histone modification | cell differentiation | positive regulation of epithelial cell proliferation | response to antibiotic | regulation of lipid transport | cellular process | epithelial tube morphogenesis | chromatin organization | developmental growth | reproductive system development | protein demethylation | negative regulation of nucleic acid-templated transcription | regulation of estradiol secretion | response to growth factor | negative regulation of cellular metabolic process | tissue development | regulation of cellular process | regulation of metabolic process | epithelium development | cellular component organization | mammary gland morphogenesis | response to stimulus | cellular response to fibroblast growth factor stimulus | gland morphogenesis | demethylase activity | regulation of cell proliferation | histone demethylase activity (H3-trimethyl-K4 specific) | regulation of mammary gland epithelial cell proliferation | tube morphogenesis | positive regulation of mammary gland epithelial cell proliferation | reproduction | negative regulation of metabolic process | protein modification process | macromolecule modification | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | mammary gland development | regulation of hormone levels | regulation of hormone secretion | regulation of gene expression | animal organ morphogenesis | regulation of nitrogen compound metabolic process | transcription corepressor activity | regulation of transcription by RNA polymerase II | histone demethylase activity (H3-K4 specific) | histone demethylase activity | cellular response to cytokine stimulus | fertilization | response to toxic substance | post-embryonic development | sensory organ development | uterus morphogenesis | regulation of cellular metabolic process | positive regulation of cell proliferation | regulation of RNA metabolic process | single fertilization | histone demethylation | protein metabolic process | DNA-binding transcription factor activity | response to organic substance | gland development | tissue morphogenesis | branching morphogenesis of an epithelial tube | anatomical structure development | developmental growth involved in morphogenesis | metabolic process | regulation of RNA biosynthetic process | histone H3-K4 demethylation | negative regulation of transcription, DNA-templated | regulation of secretion | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | mammary gland epithelium development | morphogenesis of a branching epithelium | camera-type eye development | uterus development | histone H3-K4 demethylation, trimethyl-H3-K4-specific | response to fungicide | regulation of cell communication | cellular response to leukemia inhibitory factor | covalent chromatin modification | regulation of transcription, DNA-templated | regulation of epithelial cell proliferation | cellular protein metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | histone lysine demethylation | reproductive structure development | regulation of developmental process | developmental process | organelle organization | cellular protein modification process | negative regulation of transcription by RNA polymerase II | tube development | regulation of transport | response to fibroblast growth factor | transcription coregulator activity | epithelial cell differentiation | demethylation | positive regulation of metabolic process | chromosome organization | cellular metabolic process | cellular response to organic substance | lens fiber cell differentiation | branching involved in mammary gland duct morphogenesis | sexual reproduction | lens development in camera-type eye | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | cytoplasm | intracellular organelle | histone methyltransferase complex | protein-containing complex | methyltransferase complex | nucleoplasm | transferase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
