QuickView for SRF;jsessionid=944B4FA0D423637379D3CA652C7DA341;jsessionid=9F04B2730E842CFE347C610FF4CE0441 (gene)
- Gene Symbol:
- Srf
Rattus norvegicus - Full name:
- serum response factor
- Synonyms:
- RGD1559787, serum response factor, serum response factor (c-fos serum response element-binding transcription factor)
- Genomic Location:
- Chr 9: 9788364-9797640
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-101 , Predicted Gene Targets for miR-122a , Predicted Gene Targets for miR-125 , Predicted Gene Targets for miR-142-5p , Predicted Gene Targets for miR-144 , Predicted Gene Targets for miR-150 , Predicted Gene Targets for miR-186 , Predicted Gene Targets for miR-200b , Predicted Gene Targets for miR-22 , Predicted Gene Targets for miR-28
GO Molecular Function
sequence-specific DNA binding | transcription factor activity, transcription factor binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcription factor activity, RNA polymerase II transcription factor binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | chromatin binding | serum response element binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | identical protein binding | primary miRNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | chromatin DNA binding | RNA polymerase II transcription factor binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | histone deacetylase binding | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | response to extracellular stimulus | brain development | cell morphogenesis | regulation of muscle system process | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | blastocyst formation | response to nutrient levels | actin filament-based process | long-term memory | response to cytokine | cellular response to glucose stimulus | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | positive regulation of filopodium assembly | regulation of neurogenesis | muscle tissue development | regulation of cell development | regulation of localization | heart trabecula morphogenesis | cell-substrate adhesion | actin filament bundle organization | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | erythrocyte homeostasis | eye development | hippocampus development | actin cytoskeleton organization | smooth muscle cell differentiation | blood vessel endothelial cell migration | response to hormone | myeloid cell differentiation | dorsal aorta development | neuron migration | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | epithelial structure maintenance | negative regulation of RNA biosynthetic process | bone development | cell differentiation | respiratory tube development | striated muscle cell development | nervous system development | cellular response to extracellular stimulus | regulation of smooth muscle contraction | epithelial cell migration | cellular chemical homeostasis | positive regulation of axonogenesis | neurogenesis | glucose homeostasis | generation of neurons | cardiac cell development | tissue homeostasis | blood vessel morphogenesis | pattern specification process | positive regulation of cellular biosynthetic process | regulation of transcription initiation from RNA polymerase II promoter | tangential migration from the subventricular zone to the olfactory bulb | cellular process | lymphocyte differentiation | positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation | regulation of cell motility | localization | cellular homeostasis | sarcomere organization | epithelial tube morphogenesis | mesoderm morphogenesis | heart morphogenesis | forebrain cell migration | negative regulation of signaling | developmental growth | neuron development | positive regulation of transcription from RNA polymerase II promoter involved in heart development | determination of left/right symmetry | mesoderm development | epithelium migration | immune system development | negative regulation of nucleic acid-templated transcription | learning | bronchus development | hemostasis | response to hypoxia | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | myeloid cell development | regulation of neuron projection development | transcription factor activity, RNA polymerase II transcription factor binding | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | muscle structure development | anatomical structure homeostasis | muscle cell differentiation | cell junction assembly | negative regulation of cell motility | regulation of cellular process | leukocyte activation | positive regulation of cell growth | regulation of metabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | trabecula morphogenesis | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | T cell activation | head development | sprouting angiogenesis | thyroid gland development | associative learning | branching involved in blood vessel morphogenesis | response to stimulus | thymus development | vasculature development | muscle cell development | respiratory system development | skin morphogenesis | determination of heart left/right asymmetry | mesoderm formation | response to stress | endothelial cell migration | cellular nitrogen compound biosynthetic process | heart trabecula formation | regulation of cell proliferation | vascular smooth muscle cell differentiation | multicellular organismal homeostasis | tube morphogenesis | cardiac muscle tissue development | response to glucose | telencephalon cell migration | hematopoietic progenitor cell differentiation | negative regulation of amyloid-beta clearance | supramolecular fiber organization | cardiovascular system development | cellular nitrogen compound metabolic process | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | regulation of cellular component size | positive regulation of RNA biosynthetic process | platelet formation | hemopoiesis | cellular component assembly | regulation of axon extension | mRNA metabolic process | cartilage development | modulation of chemical synaptic transmission | regulation of cell adhesion | cellular biosynthetic process | embryo development | blood vessel development | myeloid cell homeostasis | anterior/posterior pattern specification | blood coagulation | regulation of nucleic acid-templated transcription | water homeostasis | leukocyte differentiation | locomotion | organelle assembly | trachea cartilage development | regulation of cell projection assembly | system development | cellular response to nutrient levels | response to oxygen levels | nitrogen compound metabolic process | positive regulation of neuron projection development | multicellular organism development | cell migration | cellular glucose homeostasis | actin filament organization | learning or memory | regulation of axonogenesis | regulation of muscle contraction | mRNA transcription by RNA polymerase II | wound healing | trophectodermal cell differentiation | telencephalon development | artery development | determination of bilateral symmetry | regulation of neuron differentiation | regulation of gene expression | platelet activation | positive thymic T cell selection | cellular response to stress | nervous system process | platelet morphogenesis | embryonic heart tube morphogenesis | coronary vasculature development | positive regulation of cellular metabolic process | eyelid development in camera-type eye | animal organ morphogenesis | regulation of pri-miRNA transcription by RNA polymerase II | lung smooth muscle development | regulation of nitrogen compound metabolic process | olfactory lobe development | regulation of cell migration | apical junction assembly | positive regulation of cell projection organization | cardiocyte differentiation | positive regulation of protein complex assembly | regulation of cellular component movement | regulation of transcription by RNA polymerase II | response to nutrient | actin filament bundle assembly | morphogenesis of an epithelial sheet | bicellular tight junction assembly | positive regulation of cell differentiation | cognition | homeostasis of number of cells | stem cell differentiation | carbon catabolite regulation of transcription | biosynthetic process | cardiac myofibril assembly | aromatic compound biosynthetic process | cardiac muscle cell development | muscle cell cellular homeostasis | angiogenesis | actomyosin structure organization | positive regulation of pri-miRNA transcription by RNA polymerase II | heart looping | positive regulation of transcription by glucose | skin development | megakaryocyte differentiation | endocrine system development | cell morphogenesis involved in differentiation | erythrocyte development | sensory organ development | gastrulation with mouth forming second | chordate embryonic development | striated muscle tissue development | cell communication | regulation of cellular metabolic process | positive regulation of smooth muscle contraction | olfactory bulb development | anterior/posterior axis specification | contractile actin filament bundle assembly | heart development | homeostatic process | limbic system development | mRNA transcription | response to monosaccharide | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | regulation of filopodium assembly | striated muscle cell differentiation | coagulation | cell aging | embryonic morphogenesis | smooth muscle tissue development | lymphocyte activation | long term synaptic depression | positive regulation of molecular function | positive regulation of axon extension | neuron differentiation | embryonic organ morphogenesis | T cell differentiation | regulation of cell morphogenesis involved in differentiation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | cellular response to nutrient | DNA-binding transcription factor activity | regionalization | axis specification | regulation of growth | T cell selection | response to organic substance | gland development | T cell differentiation in thymus | tissue morphogenesis | artery morphogenesis | branching morphogenesis of an epithelial tube | response to wounding | regulation of DNA-binding transcription factor activity | embryonic heart tube development | anatomical structure development | positive regulation of neurogenesis | aorta development | cell projection organization | metabolic process | positive regulation of cell development | positive regulation of DNA-templated transcription, initiation | cell-cell junction assembly | regulation of RNA biosynthetic process | primitive streak formation | regulation of body fluid levels | negative regulation of transcription, DNA-templated | embryonic organ development | positive T cell selection | regulation of amyloid-beta clearance | cellular response to carbohydrate stimulus | chemical homeostasis | behavior | cell adhesion | trachea development | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | neuron projection development | positive regulation of muscle contraction | thymic T cell selection | positive regulation of cellular component biogenesis | organic substance metabolic process | regulation of water loss via skin | connective tissue development | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | forebrain development | pallium development | gene expression | epithelial cell-cell adhesion | negative regulation of cellular component movement | dorsal aorta morphogenesis | myofibril assembly | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | cytoskeleton organization | cell-cell adhesion | transcription, DNA-templated | blastocyst development | cell activation | aorta morphogenesis | lung development | morphogenesis of a branching epithelium | camera-type eye development | anatomical structure formation involved in morphogenesis | memory | cardiac muscle cell differentiation | regulation of cell communication | cellular senescence | positive regulation of developmental growth | positive regulation of growth | regulation of transcription, DNA-templated | cell-matrix adhesion | myoblast differentiation | cell development | regulation of developmental growth | regulation of cell size | cardioblast differentiation | morphogenesis of a branching structure | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of DNA-templated transcription, initiation | stress fiber assembly | positive regulation of plasma membrane bounded cell projection assembly | regulation of nervous system development | hematopoietic stem cell differentiation | regulation of developmental process | developmental process | organelle organization | erythrocyte differentiation | regulation of cell growth | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | cardiac muscle cell myoblast differentiation | cell migration involved in sprouting angiogenesis | multicellular organismal water homeostasis | positive regulation of nucleic acid-templated transcription | positive regulation of transcription via serum response element binding | lung morphogenesis | formation of primary germ layer | positive regulation of transcription by RNA polymerase II | cardiac chamber development | heterocycle metabolic process | negative regulation of synaptic transmission | regulation of transcription by glucose | regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation | central nervous system development | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | cardiac vascular smooth muscle cell differentiation | in utero embryonic development | positive regulation of metabolic process | regulation of synaptic plasticity | positive regulation of neuron differentiation | bronchus cartilage development | regulation of cell projection organization | skeletal system development | gastrulation | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | ameboidal-type cell migration | cellular response to organic substance | megakaryocyte development | response to carbohydrate | positive regulation of cell morphogenesis involved in differentiation | circulatory system development | aging | carbohydrate homeostasis | negative regulation of locomotion | negative regulation of pri-miRNA transcription by RNA polymerase II | regulation of cellular component organization | positive regulation of transcription initiation from RNA polymerase II promoter | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | cell-cell junction organization | face development
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular
