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(e.g. Pharmacogenetics, Doxycycline, rs2476601, FABP1, Apoptosis, Arthritis, Liver)
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QuickView for TOP2A (gene)


Body Atlas

Most Correlated Tissues

  1. Thymus gland
  2. Hematopoietic stem cell of bone marrow
  3. Testes
  4. Bone marrow
  5. Granulocyte-macrophage progenitor cell of bone marrow
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Disease Atlas

Most Correlated Diseases

  1. Vesicular stomatitis Indiana virus disease
  2. Epstein-Barr virus disease
  3. Brain cancer
  4. Bacterial septicemia
  5. Injury of liver
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Pharmaco Atlas

Most Correlated Compounds

  1. Teniposide
  2. Razoxane
  3. valrubicin
  4. Amsacrine
  5. Idarubicin
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. MIR103A2
  2. ECD
  3. GNAS
  4. COL7A1
  5. HIST1H1B
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Topoisomerase II deficiency leads to a postreplicative structural shift in all Saccharomyces cerevis…
  2. Negative supercoils regulate meiotic crossover patterns in budding yeast.
  3. Topoisomerase II is regulated by translationally controlled tumor protein for cell survival during o…
  4. Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joini…
  5. Topoisomerases Modulate the Timing of Meiotic DNA Breakage and Chromosome Morphogenesis in Saccharom…
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Clinical Trials

Most Relevant Clinical Trials

  1. Epirubicin or Not in Patients With TOP2A (Topoisomerase (DNA) II Alpha (170kD)) Normal Early Breast …
  2. Neoadjuvant Phase II Trial in Patients With T1c Operable, HER2-positive Breast Cancer According to T…
  3. Studying Tissue Samples From Women With Breast Cancer Who Were Treated on Clinical Trial NCCTG-N9831
  4. Standard Neoadjuvant Chemotherapy Versus Genomic Driven Chemotherapy in Patients With Breast Cancer
  5. Adj TC + Herceptin Early Stage Breast Cancer
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