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Wy 14643
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
PDK4
Acot1
ACOT2
VNN1
FABP4
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Pathway Enrichment
Most Correlated Biogroups
HSIAO_LIVER_SPECIFIC_GENES
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
MOOTHA_MITOCHONDRIA
MODULE_23
MOOTHA_HUMAN_MITODB_6_2002
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Curated Studies
Most Correlated Studies
Effect of synthetic dietary triglycerides on liver of WT and PPARα-null mice
Livers of Wild-Type and PPARalpha-Null Mice Exposed to Perfluorooctanoic Acid (PFOA)
Hepatocytes from male wistar rats treated with 14 hepatotoxicants
Toxicogenomics for the prediction of nongenotoxic hepatocarcinogenesis in rat
Livers of mice treated with genotoxic or non-genotoxic carcinogens
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Literature
Most Relevant Literature
WY-14643, a novel antiplatelet and antithrombotic agent targeting the GPIbα receptor.
Chronic Treatment With WY-14643 Induces Tumorigenesis and Triglyceride Accumulation in Mouse Livers.
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
PPARα Agonist WY-14643 Relieves Neuropathic Pain through SIRT1-Mediated Deacetylation of NF-κB.
PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic f…
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Clinical Trials
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There were no clinical trials for Wy 14643
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