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QuickView for p53 tumor suppressors
Most Correlated Studies
- Neuroblastoma SHEP cells with dox-induced/uninduced MYCN before or after nutlin-3a treatment
- Retinoblastoma gene expression among mouse models with inactivated tumor suppressor pathways
- Brain of different glioma models with specific inactivation of tumor suppressors P53, NF1 and PTEN
- HCT116 colorectal carcinoma cells in the presence and absence of tumor suppressor PTEN
- Splenic B and non B cells with or without P53 knockout mice and irradiated with 7Gy IR
Most Relevant Literature
- TP53 mutations in cancer: Molecular features and therapeutic opportunities (Review).
- p53: A tale of complexity and context.
- p53 at the crossroads of tumor immunity.
- Targeting Mutant-p53 for Cancer Treatment: Are We There Yet?
- An overview of the functions of p53 and drugs acting either on wild- or mutant-type p53.
Most Relevant Clinical Trials
- Studies of the Tumour Suppressor Gene PTEN - Endometrial Cancer
- Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.
- Role of p53 Gene in Metabolism Regulation in Patients With Li-Fraumeni Syndrome
- A Study of the Effects of PEITC on Oral Cells With Mutant p53
- P53 in Differentiated Thyroid Cancer
