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QuickView for Bacampicillin (compound)

Name: bacampicillin
PubChem Compound ID: 10782154
Molecular formula: C19H17NO4
Molecular weight: 323.343 g/mol
Name: bacampicillin
Name (isomeric): DB01602
Drug Type: small molecule
Bacampicillin Hydrochloride
Brand: Spectrobid, Penglobe
Category: Anti-Bacterial Agents, Penicillins
CAS number: 50972-17-3
Indication: For infections at the following sites: upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis, when due to sensitive strains of the following organisms: Gram-positive: streptococci (including <i>S. faecalis</i> and <i>S. pneumoniae</i>) and nonpenicillinase-producing staphylococci; Gram-negative: <i>H. influenzae</i>, <i>N. gonorrhoeae</i>, <i>E. coli</i>, <i>P. mirabilis</i>, <i>Salmonellae</i> and <i>Shigellae</i>.
Pharmacology: Bacampicillin is a prodrug of ampicillin and is microbiologically inactive.
Mechanism of Action: During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides.
Absorption: Absorbed following oral administration.
Affected organisms: Enteric bacteria and other eubacteria
Drug interaction:
Ethinyl EstradiolThis anti-infectious agent could decrease the effect of the oral contraceptive
DoxycyclinePossible antagonism of action
DemeclocyclinePossible antagonism of action
MinocyclinePossible antagonism of action
MethotrexateThe penicillin increases the effect and toxicity of methotrexate
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