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QuickView for Bacampicillin (compound)
PubChem
| Name: | bacampicillin |
|---|---|
| PubChem Compound ID: | 10782154 |
| Molecular formula: | C19H17NO4 |
| Molecular weight: | 323.343 g/mol |
DrugBank
Identification
| Name: | bacampicillin |
|---|---|
| Name (isomeric): | DB01602 |
| Drug Type: | small molecule |
| Synonyms: |
Bacampicillin Hydrochloride
|
| Brand: | Spectrobid, Penglobe |
| Category: | Anti-Bacterial Agents, Penicillins |
| CAS number: | 50972-17-3 |
Pharmacology
| Indication: | For infections at the following sites: upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis, when due to sensitive strains of the following organisms: Gram-positive: streptococci (including <i>S. faecalis</i> and <i>S. pneumoniae</i>) and nonpenicillinase-producing staphylococci; Gram-negative: <i>H. influenzae</i>, <i>N. gonorrhoeae</i>, <i>E. coli</i>, <i>P. mirabilis</i>, <i>Salmonellae</i> and <i>Shigellae</i>. |
|---|---|
| Pharmacology: | Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. |
| Mechanism of Action: | During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides. |
| Absorption: | Absorbed following oral administration. |
| Affected organisms: | Enteric bacteria and other eubacteria |
Interactions
| Drug interaction: |
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Targets
