QuickView for Dextrothyroxine (compound)

EINECS 200-102-7; O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine; 51-49-0; D-4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzylalanine; D-Thyroxine; Dextrothyroxinum; CAS-51-48-9; NCGC00016228-01; D-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-; Dextrothyroxine.
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EINECS 200-102-7; O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine; 51-49-0; D-4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzylalanine; D-Thyroxine; Dextrothyroxinum; CAS-51-48-9; NCGC00016228-01; D-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-; Dextrothyroxine; CHEBI:30659
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Dekstrotyroksiininatrium; 3,5,3′,5′-Tetraiodo-d-thyronine Sodium; Dextrothyroxinum Natricum; Dextrotiroxina sódica; Dextrotyroxinnatrium; Sodium 4-O-(4-hydroxy-3,5-di-iodophenyl)-3,5-di-iodo-d-tyrosinate hydrate; D-Thyroxine Sodium

Dextrothyroxine is a antihyperlipidemic. The mechanism of action is not completely understood, but dextrothyroxine apparently acts in the liver to stimulate formation of low-density lipoprotein (LDL) and, to a much greater extent, to increase catabolism of LDL. This leads to increased excretion of cholesterol and bile acids via the biliary route in...
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Dextrothyroxine is a antihyperlipidemic. The mechanism of action is not completely understood, but dextrothyroxine apparently acts in the liver to stimulate formation of low-density lipoprotein (LDL) and, to a much greater extent, to increase catabolism of LDL. This leads to increased excretion of cholesterol and bile acids via the biliary route into the feces, with a resulting reduction in serum cholesterol and LDL. Dextrothyroxine has no significant effect on high-density lipoproteins (HDL). Inherently, it will also bind to thyroid receptors and as it is a prohormone, it will bind as a substrate to iodide peroxidase.
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