QuickView for HOXA3 (gene)

Gene Symbol:

HOXA3 Homo sapiens

Full name:

homeobox A3

Synonyms:

HOX1, HOX1E, homeobox protein Hox-A3, Hox-1.5-like protein, homeo box 1E, homeo box A3, homeobox protein Hox-1E

Genomic Location:

Chr 7: 27112334-27133164

Description:

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcripti...

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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Rattus norvegicus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  SP1_01 ,  RTAAACA_FREAC2_01 ,  OCT1_05 ,  USF_Q6 ,  OCT1_04 ,  TGGNNNNNNKCCAR_UNKNOWN ,  EFC_Q6 ,  VDR_Q3 ,  OCT1_01 ,  MYOGNF1_01 ,  YATGNWAAT_OCT_C ,  TTTTGAG_MIR373 ,  POU3F2_01 ,  GATA_C ,  YTATTTTNR_MEF2_02 ,  CACGTG_MYC_Q2 ,  SRF_Q6 ,  CATTGTYY_SOX9_B1 ,  NKX3A_01 ,  GCANCTGNY_MYOD_Q6 ,  FOXD3_01 ,  AAANWWTGC_UNKNOWN ,  XBP1_01 ,  LYF1_01 ,  ARP1_01 ,  WGTTNNNNNAAA_UNKNOWN ,  AP2GAMMA_01 ,  MEIS1BHOXA9_01 ,  STAT6_01 ,  TTGCACT_MIR130A_MIR301_MIR130B ,  HNF1_C ,  SREBP1_Q6 ,  CTTTGA_LEF1_Q2 ,  COUP_01 ,  NKX22_01 ,  ATGGYGGA_UNKNOWN ,  PBX1_01 ,  AP2ALPHA_01 ,  EGR2_01 ,  OCT_C ,  TGACCTY_ERR1_Q2 ,  WHN_B ,  HEB_Q6 ,  HNF4_DR1_Q3 ,  WTGAAAT_UNKNOWN ,  CDP_01 ,  STAT_Q6 ,  CREBP1_Q2 ,  AR_Q6 ,  EVI1_03 ,  MYCMAX_02 ,  CEBPDELTA_Q6 ,  OCT1_Q6 ,  DBP_Q6 ,  CAGGTA_AREB6_01 ,  GTGACGY_E4F1_Q6 ,  MEF2_01 ,  RP58_01 ,  FREAC3_01 ,  RREB1_01 ,  CDX2_Q5 ,  STAT5B_01 ,  CAGGTG_E12_Q6 ,  DR1_Q3 ,  TTCYRGAA_UNKNOWN ,  EGR_Q6 ,  ZID_01 ,  HNF4_Q6 ,  EVI1_05 ,  MYCMAX_01 ,  CATRRAGC_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  TGCTGAY_UNKNOWN ,  STAT5A_03 ,  PITX2_Q2 ,  USF_C ,  SRF_Q4 ,  YKACATTT_UNKNOWN ,  OCT1_03 ,  NKX25_02 ,  FOXO1_01 ,  CTTTAAR_UNKNOWN ,  HFH4_01 ,  TGTTTGY_HNF3_Q6 ,  NRF2_Q4 ,  YCATTAA_UNKNOWN ,  RORA1_01 ,  AR_Q2 ,  GFI1_01 ,  MYB_Q6 ,  MEIS1AHOXA9_01 ,  AATGTGA_MIR23A_MIR23B ,  GCGCTTT_MIR518B_MIR518C_MIR518D ,  USF_Q6_01 ,  POU3F2_02 ,  TTGTTT_FOXO4_01 ,  AP4_Q6_01 ,  CEBP_C ,  CART1_01 ,  PIT1_Q6 ,  GATA4_Q3 ,  IK2_01 ,  GATA1_05 ,  CCAGGGG_MIR331 ,  MEF2_03 ,  COUP_DR1_Q6 ,  SMAD4_Q6 ,  CTGCAGY_UNKNOWN ,  GTGGGTGK_UNKNOWN ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  TGATTTRY_GFI1_01 ,  AP1_Q2 ,  RYAAAKNNNNNNTTGW_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  ICSBP_Q6 ,  GRE_C ,  CTTTGT_LEF1_Q2 ,  ER_Q6_02 ,  ER_Q6_01 ,  CAGCTG_AP4_Q5 ,  FOXM1_01 ,  AACTTT_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  PPAR_DR1_Q2 ,  CRX_Q4 ,  ACAGGGT_MIR10A_MIR10B ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  ERR1_Q2 ,  DR4_Q2 ,  CEBPGAMMA_Q6 ,  HNF6_Q6 ,  SRF_C ,  TCF11_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-10 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-330 ,  Predicted Gene Targets for miR-331 ,  Predicted Gene Targets for miR-338 ,  Predicted Gene Targets for miR-375

Cytogenetic Map:

7p15.2

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