QuickView for Mitoxantrone (compound)

KBio2_007271; AN-584/42007670; Lopac-M-6545; 5,8-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)-1,4-dihydroxyanthraquinone; 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)- (9CI); KBio1_000516; Mitozantrone; 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-; 70711-41-0; 137635-96-2.
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KBio2_007271; AN-584/42007670; Lopac-M-6545; 5,8-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)-1,4-dihydroxyanthraquinone; 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)- (9CI); KBio1_000516; Mitozantrone; 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-; 70711-41-0; 137635-96-2; 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione; C11195; Dihydroxyanthraquinone; KBio2_002135; KBioSS_002135; Novantron; AIDS-005213; Mitoxantrone; MITOXANTRONE, 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)ANTHRA-9,10-QUINONE; 1,4-Dihydroxy-5,8-bis(5-hydroxy-3-azapentylamino)anthrachinon; DHAQ; CAS-70476-82-3; Mitoxantron; AIDS005213; Spectrum_001655; 70945-62-9; NSC299195; NSC279836; DHAD; NCI60_002276; 1,4-Bis(2-(2-hydroxyethylamino)ethyl)amino)-5,8-dihydroxyanthraquinone; KBioGR_001531; MIX; CCRIS 7604; Prestwick0_000385; Mitoxanthrone; Prestwick1_000385; 65271-80-9; Spectrum3_001590; Mitoxantrone (free base); 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE; Mitox; NSC301739; NCGC00015693-02; NCGC00015693-01; ANTHRAQUINONE, 5,8-BIS((2-((2-HYDROXYETHYL)AMINO)ETHYL)AMINO)-1,4-DIHYDROXY-; BRN 2795126; Mitoxantronum [INN-Latin]; Mitoxantrona [INN-Spanish]; Spectrum2_000908; DHAQ HCl; SPBio_002490; DivK1c_000516; DHAQ (*Diacetate salt*); KBio2_004703; NSC 279836; 9, 10-Anthracenedione, 1,4-dihydroxy-5, 8-bis[[2-[(2-hydroxyethyl)amino]ethyl] amino]-; Spectrum4_000866; 9,10-Anthracenedione, 1, 4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl] amino]-, dihydrochloride; 70476-82-3; KBio3_002660; SPBio_000756; NINDS_000516; 1,4-Dihydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione; NCI60_002535
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Mitoxantrone dihydrochloride; Mitozantrone hydrochloride; Mitoxantrone 2HCl; Mitoxanthrone; DHAQ HCl; DHAQ; Mitoxantron; Mitozantrone; Mitoxantrone HCl; Dihydroxyanthraquinone.
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Mitoxantrone dihydrochloride; Mitozantrone hydrochloride; Mitoxantrone 2HCl; Mitoxanthrone; DHAQ HCl; DHAQ; Mitoxantron; Mitozantrone; Mitoxantrone HCl; Dihydroxyanthraquinone; Mitoxantrone hydrochloride; DHAD; Mitoxantronum [INN-Latin]; Mitoxantrona [INN-Spanish]
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Mitoxantrone, a DNA-reactive agent that intercalates into deoxyribonucleic acid (DNA) through hydrogen bonding, causes crosslinks and strand breaks. Mitoxantrone also interferes with ribonucleic acid (RNA) and is a potent inhibitor of topoisomerase II, an enzyme responsible for uncoiling and repairing damaged DNA. It has a cytocidal effect on both ...
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Mitoxantrone, a DNA-reactive agent that intercalates into deoxyribonucleic acid (DNA) through hydrogen bonding, causes crosslinks and strand breaks. Mitoxantrone also interferes with ribonucleic acid (RNA) and is a potent inhibitor of topoisomerase II, an enzyme responsible for uncoiling and repairing damaged DNA. It has a cytocidal effect on both proliferating and nonproliferating cultured human cells, suggesting lack of cell cycle phase specificity.
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