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QuickView for carbachol (compound)

Name: Carbachol
PubChem Compound ID: 2551
Description: A slowly hydrolyzed cholinergic agonist that acts at both muscarinic and nicotinic receptors.
Molecular formula: C6H15N2O2+
Molecular weight: 147.196 g/mol
2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium; Carbocholine; Choline, carbonate (ester); DivK1c_000725; Prestwick0_000880; Prestwick1_000880; Doryl; KBio2_000514; Carbamiotin; Spectrum2_000114.
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Name: Carbachol
Name (isomeric): DB00411
Drug Type: small molecule
Description: A slowly hydrolyzed cholinergic agonist that acts at both muscarinic and nicotinic receptors.
Brand: Choline chlorine carbamate, Mistura C, Karbachol, Carbachol hydrochloride, Lentin, CB, Jestryl, Carbastat intraocular, Moryl, Carbochol, Carbamoylcholine-hydrochloride, Carbamoylcholine chloride, Carbaminocholine chloride, Karbamoylcholin chlorid, Rilentol, Doryl, Carcholin, Carbocholine, Choline carbamate chloride, Carbacolina, Carbacholin, Isopto Carbachol, Carbachol chloride, Lentine, Carbachol USP27, P. V. Carbachol, Miostat, Carbyl, Coletyl, Carbacholine chloride, Carbaminoylcholine chloride, Carbastat, Choline chloride, carbamoyl-, Vasoperif, Carbamylcholine chloride, Carbacholine, Carbamiotin, Carbocholin, Choline chloride carbamate, Choline, chloride, carbamate, Carboptic
Category: Cholinergic Agonists, Analgesics, Non-Narcotic, Cardiotonic Agents, Miotics
CAS number: 51-83-2
Indication: Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (RE...
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Mechanism of Action: Carbachol is a parasympathomimetic that stimulates both muscarinic and nicotinic receptors. In topical ocular and intraocular administration its principal effects are miosis and increased aqueous humour outflow.
Absorption: Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Toxicity: Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Affected organisms: Humans and other mammals
Drug interaction:
TacrineThe acetylcholinesterase inhibitor, Tacrine, may increase the cholinergic effects of Carbachol, a cholinergic agonist. Monitor for increased cholinergic effects.