QuickView for IRF3;jsessionid=FDC9B297150043FDE1E65492099BBEB5;jsessionid=6FB6F3457CFACA70A7C493C0EB30DE97;jsessionid=B7651BCF6290CD877624AF5276A04158 (gene)
- Gene Symbol:
- Irf3
Rattus norvegicus - Full name:
- interferon regulatory factor 3
- Synonyms:
- interferon regulatory factor 3
- Genomic Location:
- Chr 1: 95470284-95475078
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Canis lupus familiaris , Bos taurus , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | protein domain specific binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | identical protein binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
positive regulation of immune response | RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | response to virus | negative regulation of immune system process | response to lipopolysaccharide | negative regulation of type I interferon production | regulation of localization | defense response to other organism | regulation of immune system process | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | negative regulation of RNA biosynthetic process | regulation of interferon-beta biosynthetic process | defense response | positive regulation of protein secretion | positive regulation of cellular biosynthetic process | cellular process | response to exogenous dsRNA | regulation of cytokine biosynthetic process | programmed necrotic cell death | negative regulation of nucleic acid-templated transcription | regulation of response to cytokine stimulus | regulation of defense response to virus | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of interferon-beta production | regulation of immune response | regulation of cellular process | cellular response to lipid | regulation of metabolic process | cellular response to molecule of bacterial origin | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | positive regulation of type I interferon-mediated signaling pathway | regulation of peptide secretion | regulation of type I interferon production | response to stimulus | positive regulation of innate immune response | positive regulation of immune system process | response to stress | cellular nitrogen compound biosynthetic process | programmed cell death | positive regulation of cytokine secretion | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | regulation of protein transport | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | regulation of peptide transport | cellular biosynthetic process | negative regulation of interferon-beta biosynthetic process | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | positive regulation of response to cytokine stimulus | response to nitrogen compound | negative regulation of defense response to virus | response to external biotic stimulus | nitrogen compound metabolic process | regulation of signal transduction | response to dsRNA | type I interferon production | negative regulation of defense response to virus by host | regulation of gene expression | positive regulation of secretion | response to lipid | negative regulation of cytokine production | positive regulation of cellular metabolic process | defense response to virus | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | biosynthetic process | aromatic compound biosynthetic process | negative regulation of cytokine biosynthetic process | response to bacterium | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | cellular response to dsRNA | positive regulation of establishment of protein localization | regulation of cytokine-mediated signaling pathway | regulation of RNA metabolic process | lipopolysaccharide-mediated signaling pathway | positive regulation of transport | positive regulation of interferon-alpha production | negative regulation of interferon-beta production | regulation of cytokine secretion | cytokine production | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | protein metabolic process | DNA-binding transcription factor activity | regulation of establishment of protein localization | response to organic substance | regulation of innate immune response | regulation of intracellular signal transduction | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | type I interferon biosynthetic process | regulation of secretion | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | cell death | negative regulation of biosynthetic process | regulation of type I interferon-mediated signaling pathway | negative regulation of gene expression | gene expression | regulation of protein secretion | transcription, DNA-templated | positive regulation of cytokine production | positive regulation of protein transport | negative regulation of protein metabolic process | positive regulation of cytokine-mediated signaling pathway | regulation of cell communication | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of cytokine production | cellular macromolecule biosynthetic process | response to biotic stimulus | cytokine biosynthetic process | negative regulation of transcription by RNA polymerase II | regulation of transport | positive regulation of transcription, DNA-templated | necrotic cell death | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | regulation of defense response to virus by host | cytokine metabolic process | heterocycle metabolic process | positive regulation of metabolic process | immune system process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | positive regulation of type I interferon production | regulation of I-kappaB kinase/NF-kappaB signaling | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to lipopolysaccharide | macromolecule metabolic process | positive regulation of interferon-beta production | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular
