QuickView for NFKB1;jsessionid=59F8CD6A178175E43595B79F80C4160E;jsessionid=C661026CF46E9F58A39F144F6D13F3F0;jsessionid=BBFE6830E666E603D2E995AFE0116431;jsessionid=4442B1A87DD452F2CEEE89B7C5D1D5A4;jsessionid=E834F6C9A23C2ECC0C91C8F676BFDDC4 (gene)
- Gene Symbol:
- Nfkb1
Mus musculus - Full name:
- nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
- Synonyms:
- NF-KB1, NF-kappaB, NF-kappaB1, p105, p50, p50/p105, nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1, EBP-1, NF kappaB1, NF-kappa-B1 p84/NF-kappa-B1 p98, NF-kappaB p50, nuclear factor kappaB p50, nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, p50 subunit of NF kappaB
- Genomic Location:
- Chr 3: 135247619-135354511
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | enhancer binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | chromatin binding | cytoskeletal protein binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | identical protein binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | heat shock protein binding | actinin binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of hyaluronan biosynthetic process | positive regulation of macromolecule biosynthetic process | response to cytokine | response to interleukin-1 | response to lipopolysaccharide | negative regulation of vitamin D biosynthetic process | regulation of carbohydrate metabolic process | regulation of programmed cell death | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cellular response to tumor necrosis factor | regulation of vitamin metabolic process | response to drug | positive regulation of cellular biosynthetic process | cellular process | negative regulation of inflammatory response | regulation of cytokine biosynthetic process | immune system development | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | negative regulation of lipid biosynthetic process | response to growth factor | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | negative regulation of cellular metabolic process | response to peptide hormone | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | cellular response to molecule of bacterial origin | response to nerve growth factor | organic cyclic compound metabolic process | RNA biosynthetic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | regulation of gene silencing by miRNA | cellular response to glucoside | response to stimulus | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | positive regulation of miRNA metabolic process | response to stress | cellular nitrogen compound biosynthetic process | response to peptide | response to muscle stretch | programmed cell death | response to molecule of bacterial origin | regulation of gene silencing | cellular nitrogen compound metabolic process | cellular response to toxic substance | cellular response to organic cyclic compound | regulation of calcidiol 1-monooxygenase activity | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | regulation of steroid biosynthetic process | cellular biosynthetic process | regulation of steroid metabolic process | regulation of nucleic acid-templated transcription | response to nitrogen compound | apoptotic process | cellular response to interleukin-6 | cellular response to hormone stimulus | response to nicotine | response to external biotic stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | negative regulation of catalytic activity | negative regulation of calcidiol 1-monooxygenase activity | cellular response to peptide hormone stimulus | response to dsRNA | regulation of catalytic activity | cellular response to nerve growth factor stimulus | regulation of hormone levels | regulation of miRNA metabolic process | regulation of gene expression | response to lipid | cellular response to peptide | negative regulation of cytokine production | positive regulation of cellular metabolic process | cellular response to diterpene | regulation of pri-miRNA transcription by RNA polymerase II | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | response to oxidative stress | cellular response to cytokine stimulus | negative regulation of interleukin-12 production | biosynthetic process | regulation of hormone metabolic process | aromatic compound biosynthetic process | positive regulation of pri-miRNA transcription by RNA polymerase II | response to toxic substance | cellular response to angiotensin | negative regulation of cytokine biosynthetic process | cellular response to drug | response to bacterium | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | cellular response to dsRNA | regulation of RNA metabolic process | regulation of lipid biosynthetic process | regulation of hyaluronan biosynthetic process | cellular response to nicotine | negative regulation of monooxygenase activity | lymph node development | response to angiotensin | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | response to organic substance | response to glycoside | response to mechanical stimulus | anatomical structure development | negative regulation of lipid metabolic process | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | cellular response to carbohydrate stimulus | regulation of gene silencing by RNA | nucleobase-containing compound metabolic process | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | cellular response to brain-derived neurotrophic factor stimulus | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | regulation of Wnt signaling pathway | transcription, DNA-templated | positive regulation of canonical Wnt signaling pathway | negative regulation of protein metabolic process | positive regulation of carbohydrate metabolic process | negative regulation of hormone biosynthetic process | regulation of cell communication | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | regulation of oxidoreductase activity | response to organic cyclic compound | regulation of cytokine production | cellular macromolecule biosynthetic process | response to biotic stimulus | positive regulation of gene silencing by miRNA | developmental process | negative regulation of interleukin-12 biosynthetic process | negative regulation of steroid metabolic process | cellular response to interleukin-1 | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | negative regulation of oxidoreductase activity | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | regulation of interleukin-12 biosynthetic process | regulation of lipid metabolic process | positive regulation of metabolic process | immune system process | positive regulation of Wnt signaling pathway | cellular metabolic process | hematopoietic or lymphoid organ development | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | response to carbohydrate | response to interleukin-6 | negative regulation of cell death | regulation of inflammatory response | response to glucoside | negative regulation of steroid biosynthetic process | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | regulation of hormone biosynthetic process | cellular response to growth factor stimulus | cellular response to lipopolysaccharide | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | neuron projection | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | cell projection | nucleoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
