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Gene Symbol:
TAL2 Homo sapiens Homo sapiens
Full name:
TAL bHLH transcription factor 2
Synonyms:
T-cell acute lymphocytic leukemia protein 2, T-cell acute lymphocytic leukemia 2, TAL-2, class A basic helix-loop-helix protein 19
Genomic Location:
Chr 9: 107464599-107464925
Description:
This intronless gene encodes a helix-loop-helix protein. Translocations between this gene on chromosome 9 and the T-cell receptor beta-chain locus on chromosome 7 have been associated with activation of the T-cell acute lymphocytic leukemia 2 gene and T-cell acute lymphoblastic leukemia.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 9
9q31.2


Transcripts Names
NM_005421
Protein Names
Q16559
A0AVI7



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nucleic acid binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | double-stranded DNA binding | DNA-binding transcription factor activity | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | brain development | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nervous system development | multicellular organism growth | cellular process | developmental growth | diencephalon development | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | head development | cellular nitrogen compound biosynthetic process | midbrain development | cellular nitrogen compound metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | multicellular organism development | thalamus development | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | post-embryonic development | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | forebrain development | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | developmental process | heterocycle metabolic process | central nervous system development | cellular metabolic process | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular