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QuickView for p53 tumor suppressor (gene)


Body Atlas

Most Correlated Tissues

  1. B lymphocyte (IgM memory) of spleen
  2. Granulocyte-macrophage progenitor cell of bone marrow
  3. Nipple cross-section
  4. Tonsil
  5. Endometrium
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Disease Atlas

Most Correlated Diseases

  1. Neurocutaneous syndrome
  2. Disorder of intraocular pressure
  3. Parvovirus infection
  4. Chondrodysplasia
  5. Polyp of intestine
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Pharmaco Atlas

Most Correlated Compounds

  1. P2 protein, Sulfolobus
  2. AS 1411
  3. Seminal Plasma Proteins
  4. MART-1 Antigen
  5. Colcemide
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. MIR424
  2. SART3
  3. EIF5A
  4. CDKN1A
  5. DMRT1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Dissociating the metabolic and tumor-suppressive activity of p53.
  2. TP53 mutations in cancer: Molecular features and therapeutic opportunities (Review).
  3. 53BP1-mediated activation of the tumor suppressor p53.
  4. Drugging p53: Barriers, Criteria, and Prospects.
  5. p53: A tale of complexity and context.
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Clinical Trials

Most Relevant Clinical Trials

  1. Studies of the Tumour Suppressor Gene PTEN - Endometrial Cancer
  2. Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.
  3. Role of p53 Gene in Metabolism Regulation in Patients With Li-Fraumeni Syndrome
  4. A Study of the Effects of PEITC on Oral Cells With Mutant p53
  5. P53 in Differentiated Thyroid Cancer
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