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QuickView for Pivmecillinam (compound)
PubChem
| Name: | Amdinocillin Pivoxil |
|---|---|
| PubChem Compound ID: | 115162 |
| Description: | Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. |
| Molecular formula: | C21H34ClN3O5S |
| Molecular weight: | 476.031 g/mol |
| Synonyms: |
Melysin; EINECS 251-278-7; Pivmecillinam hydrochloride (JP15); Pivmecilinamo clorhidrato [Spanish]; Selexid; FL-1039; D01499; Melysin (TN); 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((hexahydro-1H-azepin-1-yl)methylene)amino)-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, (2S,5R,6R)-; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((hexahydro-1H-azepin-1-yl)methylene)amino)-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, (2S-(2alpha,5alpha,6beta))-.
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DrugBank
Identification
| Name: | Amdinocillin Pivoxil |
|---|---|
| Name (isomeric): | DB01605 |
| Drug Type: | small molecule |
| Description: | Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. |
| Synonyms: |
Amdinocillin pivoxil; Pivmecillinamum [inn-latin]; Pivmecilinamo [inn-spanish]
|
| Brand: | Selexid, Coactabs |
| Category: | Anti-Bacterial Agents, Penicillins, Anti-Infective Agents, Urinary |
| CAS number: | 32886-97-8 |
Pharmacology
| Indication: | Used to treat infections due to mecillinam-sensitive organisms such as urinary tract infections, salmonellosis and typhoid fever. |
|---|---|
| Pharmacology: | Pivmecillinam is a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. |
| Mechanism of Action: | Pivmecillinam interferes with the biosynthesis of the bacterial cell wall however its activity is slightly different from that of other penicillins and cephalosporins |
| Absorption: | Well absorbed following oral administration. |
| Affected organisms: | Enteric bacteria and other eubacteria |
Interactions
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Targets
