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deferoxamine
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
NDRG1
CA9
SERPINE1
BNIP3
CXCL1
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Pathway Enrichment
Most Correlated Biogroups
KRIEG_HYPOXIA_NOT_VIA_KDM3A
HALLMARK_HYPOXIA
ELVIDGE_HYPOXIA_UP
ELVIDGE_HYPOXIA_BY_DMOG_UP
ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN
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Curated Studies
Most Correlated Studies
Myoblast C2C12 cells overexpressing GFP-tagged PGC-1a and treated with chelator deferoxamine
Iron chelation in regulation of gene expression in DMS-53 small cell lung carcinoma cells
Effect of hypoxia (1% O2) and hypoxia mimics (cobalt chloride, deferoxamine and nickel chloride)
HeLa cell expression after treatment with V-ATPase inhibitors, chelating iron, and low LDL
Colorectal cancer SW 480 cells treated with iron chelators deferasirox or desferrioxamine
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Literature
Most Relevant Literature
Desferrioxamine-related ocular toxicity: a case report.
Divergent effects of desferrioxamine on bacterial growth and characteristics.
Neuroprotection of desferrioxamine in lipopolysaccharide-induced nigrostriatal dopamine …
Enhanced cellular uptake and gene delivery of glioblastoma with deferoxamine-coated nanoparticle/pla…
Oxidative stress induced by arsenopyrite and the role of desferrioxamine-B as radical scavenger.
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Most Relevant Clinical Trials
Deferoxamine and Xingnaojing Injection Treatment in Intracerebral Hemorrhage
Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial
High-Dose Deferoxamine in Intracerebral Hemorrhage
Thrombolysis and Deferoxamine in Middle Cerebral Artery Occlusion
Deferoxamine In the Treatment of Aneurysmal Subarachnoid Hemorrhage (aSAH)
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