Name: | bevantolol |
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PubChem Compound ID: | 2372 |
Molecular formula: | C20H27NO4 |
Molecular weight: | 345.433 g/mol |
Synonyms: |
1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol; Bevantololum [INN-Latin]; 2-Propanol, 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-; NSC132348; 42864-78-8; BRN 2769444; 1-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol; 59170-23-9; Bevantolol
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Name: | bevantolol |
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Name (isomeric): | DB01295 |
Drug Type: | small molecule |
Synonyms: |
1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol; Bevantololum [inn-latin]
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Category: | Calcium Channel Blockers, Adrenergic beta-Antagonists, Antihypertensive Agents |
CAS number: | 59170-23-9 |
Indication: | For the treatment of angina pectoris and hypertension. |
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Pharmacology: | Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. |
Mechanism of Action: |
Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors. By binding and antagonizing beta-1 receptors Bevantolol inhibits the normal normal epinephrine-mediated sympathetic actions such as increased heart rate. This has the effect of decreasing preload and blood press...
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Affected organisms: | Humans and other mammals |
Drug interaction: |
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