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QuickView for Bevantolol (compound)


PubChem
Name: bevantolol
PubChem Compound ID: 2372
Molecular formula: C20H27NO4
Molecular weight: 345.433 g/mol
Synonyms:
1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol; Bevantololum [INN-Latin]; 2-Propanol, 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-; NSC132348; 42864-78-8; BRN 2769444; 1-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol; 59170-23-9; Bevantolol
DrugBank
Identification
Name: bevantolol
Name (isomeric): DB01295
Drug Type: small molecule
Synonyms:
1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol; Bevantololum [inn-latin]
Category: Calcium Channel Blockers, Adrenergic beta-Antagonists, Antihypertensive Agents
CAS number: 59170-23-9
Pharmacology
Indication: For the treatment of angina pectoris and hypertension.
Pharmacology: Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension.
Mechanism of Action:
Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors. By binding and antagonizing beta-1 receptors Bevantolol inhibits the normal normal epinephrine-mediated sympathetic actions such as increased heart rate. This has the effect of decreasing preload and blood press...
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Affected organisms: Humans and other mammals
Interactions
Drug interaction:
FenoterolAntagonism
IbuprofenRisk of inhibition of renal prostaglandins
PipobromanAntagonism
RepaglinideThe beta-blocker, bevantolol, may decrease symptoms of hypoglycemia.
OrciprenalineAntagonism
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Targets