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QuickView for Dihydroergotoxine (compound)
PubChem Substance
| Name: | Dihydroergotoxine |
|---|---|
| PubChem Substance ID: | 168192 |
| Description: | A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES. |
| Synonyms: |
Dihydroergotoxin; DIHYDROERGOTOXINE; Ergoloid dihydroergotoxine; Ergotoxine, dihydro-; 11032-41-0
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DrugBank
Identification
| Name: | Dihydroergotoxine |
|---|---|
| Name (isomeric): | DB01287 |
| Drug Type: | small molecule |
| Description: | A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES. |
| CAS number: | 11032-41-0 |
Pharmacology
| Indication: | For potential use in the treatment of Alzheimer's disease. |
|---|---|
| Pharmacology: | The drug may compensate for neurotransmitter deficits and can in different circumstances, compensate for hyperactivity in the same neurotransmitter pathways. The drug can counteract and prevent disturbances between monoaminergic and other transmitter systems in the CNS. |
| Mechanism of Action: |
Dihydroergotoxine is a mixture of three different ergotaman-3',6',18-triones, dihydroergocornine, dihydroergocristine, and dihydroergocryptine. It has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. Spec...
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Interactions
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Targets
