Name: | Vitamin E |
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PubChem Compound ID: | 10741418 |
Description: | A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS. |
Molecular formula: | C29H50O2 |
Molecular weight: | 432.699 g/mol |
Name: | Vitamin E |
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Name (isomeric): | DB00163 |
Drug Type: | small molecule |
Description: | A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS. |
Synonyms: |
alpha-Tocopherol; Tocopherol
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Brand: | Gordo-Vite E, E-Vitamin succinate, Vitamin Plus E Softgells, E-Ferol, Daltose, Vitec, E-200 I.U. Softgels, Aquasol E, E-Complex-600, Amino-Opti-E |
Category: | Vitamins/minerals, Micronutrient, Antioxidants, Vitamins, Dietary supplement |
CAS number: | 59-02-9 |
Indication: | Vitamin E, known for its antioxidant activities, is protective against cardiovascular disease and some forms of cancer and has also demonstrated immune-enhancing effects. It may be of limited benefit in some with asthma and rheumatoid arthritis. It may be helpful in some neurological diseases including Alzheimer's, some eye disorders including cataracts, and diabetes and premenstrual syndrome. It may also help protect skin from ultraviolet irradiation although claims that it reverses skin aging, enhances male fertility and exercise performance are poorly supported. It may help relieve some muscle cramps. |
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Pharmacology: |
Vitamin E has antioxidant activity. It may also have anti-atherogenic, antithrombotic, anticoagulant, neuroprotective, antiviral, immunomodulatory, cell membrane-stabilizing and antiproliferative actions. Vitamin E is a collective term used to describe eight separate forms, the best-known form being alpha-tocopherol. Vitamin E is a fat-soluble vita...
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Mechanism of Action: |
Although all forms of Vitamin E exhibit antioxidant activity, it is known that the antioxidant activity of vitamin E is not sufficient to explain the vitamin's biological activity.
Vitamin E's anti-atherogenic activity involves the inhibition of the oxidation of LDL and the accumulation of oxLDL in the arterial wall. It also appears to reduce ... show more » |
Absorption: | 50 to 80% absorbed from gastrointestinal tract. |
Protein binding: | Bound to beta-lipoproteins in blood. |
Biotransformation: | Hepatic. |
Affected organisms: | Humans and other mammals |
Drug interaction: |
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