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QuickView for Procaterol (compound)


PubChem
Name: Procaterol
PubChem Compound ID: 43091
Description: A long-acting beta-2-adrenergic receptor agonist.
Molecular formula: C16H23ClN2O3
Molecular weight: 326.818 g/mol
Synonyms:
2(1H)-Quinolinone, 8-hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-, monohydrochloride, (R*,S*), (+-)-; Pro-Air; 62929-91-3; Meptin; (+-)-erythro-8-Hydroxy-5-(1-hydroxy-2-(isopropylamino)butyl)carbostyril monohydrochloride; 59828-07-8; 60443-17-6; 5-(1-Hydroxy-2-isopropylamino)butyl-8-hydroxycarbostyril hydrochloride; 2(1H)-Quinolinone, 8-hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-, monohydrochloride, (R*,S*)-(+-)-; (R*,S*)-(1)-8-Hydroxy-5-(1-hydroxy-2-(isopropylamino)butyl)quinolin-2(1H)-one monohydrochloride.
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DrugBank
Identification
Name: Procaterol
Name (isomeric): DB01366
Drug Type: small molecule
Description: A long-acting beta-2-adrenergic receptor agonist.
Brand: Pro-Air
Category: Adrenergic beta-Agonists, Sympathomimetics, Bronchodilator Agents
CAS number: 72332-33-3
Pharmacology
Indication: For the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Pharmacology: Procaterol is a long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Mechanism of Action: Beta(2)-receptor stimulation in the lung causes relaxation of bronchial smooth muscle, bronchodilation, and increased bronchial airflow.
Absorption: Because of the small therapeutic dose, systemic levels of salmeterol are low or undetectable after inhalation of recommended doses.
Toxicity: Symptoms of overdose include angina (chest pain), dizziness, dry mouth, fatigue, flu-like symptoms, headache, heart irregularities, high or low blood pressure, high blood sugar, insomnia, muscle cramps, nausea, nervousness, rapid heartbeat, seizures, and tremor.
Affected organisms: Humans and other mammals
Interactions
Drug interaction:
PhenelzineIncreased arterial pressure
ReserpineIncreased arterial pressure
DesipramineThe tricyclic antidepressant, desipramine, increases the sympathomimetic effect of procaterol.
CarvedilolAntagonism
NadololAntagonism
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Targets